Role of Graphene Family Nanomaterials in Skin Wound Healing and Regeneration

Iruthayapandi Selestin Raja; Hee Jeong Jang; Moon Sung Kang; Ki Su Kim; Yu Suk Choi; Jong-Rok Jeon; Jong Hun Lee; Dong-Wook Han

doi:10.1007/978-981-16-4923-3_5

Role of Graphene Family Nanomaterials in Skin Wound Healing and Regeneration

Adv Exp Med Biol. 2022:1351:89-105. doi: 10.1007/978-981-16-4923-3_5.

Authors

Iruthayapandi Selestin Raja¹, Hee Jeong Jang², Moon Sung Kang², Ki Su Kim^{3

4}, Yu Suk Choi⁵, Jong-Rok Jeon⁶, Jong Hun Lee⁷, Dong-Wook Han⁸

Affiliations

¹ BIO-IT Fusion Technology Research Institute, Pusan National University, Busan, South Korea.
² Department of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan, South Korea.
³ School of Chemical Engineering, College of Engineering, Pusan National University, Busan, South Korea.
⁴ Institute of Advanced Organic Materials, Pusan National University, Busan, South Korea.
⁵ School of Human Sciences, The University of Western Australia, Crawley, WA, Australia.
⁶ Department of Agricultural Chemistry and Food Science & Technology, Institute of Agriculture and Life Science, Gyeongsang National University, Jinju, South Korea.
⁷ Department of Food Science and Biotechnology, Gachon University, Seongnam, South Korea.
⁸ Department of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, Busan, South Korea. nanohan@pusan.ac.kr.

PMID: 35175613
DOI: 10.1007/978-981-16-4923-3_5

Abstract

Owing to astonishing properties such as the large surface area to volume ratio, mechanical stability, antimicrobial property, and collagen crosslinking, graphene family nanomaterials (GFNs) have been widely used in various biomedical applications including tissue regeneration. Many review literatures are available to compile the role of GFNs in cardiac, bone, and neuronal tissue regeneration. However, the contribution of GFNs in skin wound healing and tissue regeneration was not yet discussed. In the present review, we have highlighted the properties of GFNs and their application in skin wound healing. In addition, we have included challenges and future directions of GFNs in skin tissue regeneration in the portion of conclusion and perspectives.

Keywords: Diabetic wound; Graphene family nanomaterials; Infection wound; Normal skin wound; Skin tissue regeneration.

Publication types

Review

MeSH terms

Graphite*
Nanostructures*
Skin
Wound Healing

Substances

Graphite