Safety and efficacy of nimodipine combined with flunarizine in patients with angioneurotic headache

Tao Zhang; Yao Xiao; Shengquan Li

Safety and efficacy of nimodipine combined with flunarizine in patients with angioneurotic headache

Am J Transl Res. 2022 Jan 15;14(1):511-517. eCollection 2022.

Authors

Tao Zhang¹, Yao Xiao², Shengquan Li¹

Affiliations

¹ Department of Neurology, Qijiang District People's Hospital Qijiang 401420, Chongqing, China.
² Medical Equipment Department of Chongqing Qijiang District People's Hospital Qijiang 401420, Chongqing, China.

PMID: 35173871
PMCID: PMC8829639

Abstract

Objective: To observe the role of nimodipine combined with flunarizine on angioneurotic headache.

Methods: Altogether 101 patients with angioneurotic headache were divided into the control group (CG, n=51) and the therapy group (TG, n=50). Patients in the CG were given nimodipine, while patients in the TG were given flunarizine on the basis of nimodipine. The clinical efficacy and adverse reactions of patients were observed.

Results: After treatment, the Visual analog scale (VAS) scores of the TG were markedly lower than those in the CG, and the number of attacks and headache duration of patients in the TG were also markedly reduced. Observation of the clinical efficacy showed that the effective rate of the TG was markedly higher than that of the CG, but no additional adverse reactions were found. In addition, after treatment, the cerebral hemodynamics and quality of life of patients were improved.

Conclusion: Nimodipine combined with flunarizine can better promote the recovery of patients with angioneurotic headache and improve their quality of life.

Keywords: Angioneurotic headache; flunarizine; nimodipine.