Design and fabrication of novel flexible sensor based on 2D Ni-MOF nanosheets as a preliminary step toward wearable sensor for onsite Ni (II) ions detection in biological and environmental samples

Abstract

Herein, for the first time, an innovative and sensitive flexible sensor for efficient potentiometric monitoring of Ni (II) ions has been designed and developed. The developed flexible sensor is constructed from highly porous activated flexible carbon cloth decorated with nitrogen and spherical porous carbon nanoparticles derived from low-cost cotton doped with polypyrrole nanoparticles via simple carbonization-activation process followed by dip-coating in membrane cocktail containing 2D Ni-MOF nanosheets as an electroactive material. The developed flexible sensor affords rapid, accurate and stable response for the Ni (II) ions monitoring at its trace level in the biological fluids including human saliva and sweat samples in addition to tap water as an environmental sample without any preconditioning steps over pH range of 2-8 with detection limit of 2.7 × 10^-6. Additionally, the flexible sensor shows good antibacterial properties against both of Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria presenting safe handling for human skin as a flexible sensor for wearable system applications. This study presents a forward step for the fabrication of a wearable sensor for rapid onsite monitoring of Ni (II) ions in biological and environmental samples.

Keywords: 2D Ni-MOF nanosheets; Antibacterial; Biological samples; Flexible sensors; Ni (II) ions; Potentiometric detection.