Cardiovascular System during SARS-CoV-2 Infection

Int J Environ Res Public Health. 2022 Jan 21;19(3):1184. doi: 10.3390/ijerph19031184.

Abstract

SARS-CoV-2 virus can not only damage the respiratory system but may also pose a threat to other organs, such as the heart or vessels. This review focuses on cardiovascular complications of COVID-19, including acute cardiac injury, arrhythmias, biomarkers, accompanying comorbidities and outcomes in patients diagnosed with SARS-CoV-2 infection. The research was conducted on the databases: PubMed, Springer, ScienceDirect, UpToDate, Oxford Academic, Wiley Online Library, ClinicalKey. Fifty-six publications from 1 November 2020 till 15 August 2021 were included in this study. The results show that cardiac injury is present in about 1 in 4 patients with COVID-19 disease, and it is an independent risk factor, which multiplies the death rate several times in comparison to infected patients without myocardial injury. New-onset cardiac injury occurs in nearly every 10th patient of the COVID-19-suffering population. Comorbidities (such as hypertension, cardiovascular disease and diabetes) severely deteriorate the outcome. Therefore, patients with SARS-CoV-2 infection should be carefully assessed in terms of cardiac medical history and possible cardiological complications.

Keywords: cardiac complications; cardiac injury; coronavirus disease 2019; prognosis; troponin.

Publication types

  • Review

MeSH terms

  • COVID-19*
  • Cardiovascular Diseases* / epidemiology
  • Heart
  • Heart Diseases*
  • Humans
  • SARS-CoV-2