Influence of parameters on mechanical properties of poly (L-lactic acid) helical stents

J Biomed Mater Res B Appl Biomater. 2022 Jul;110(7):1705-1712. doi: 10.1002/jbm.b.35031. Epub 2022 Feb 14.

Abstract

With better biocompatibility, bioresorbable poly (L-lactic acid) (PLLA) helical stents are expected to replace the commonly used metallic stents. However, due to the great difference between the material properties of PLLA and those of metals, the current research results on mechanical properties of stents will not be applicative. In this article, the effects of i on the radial compression performance and bending stiffness of PLLA helical stents were systematically studied, and the effect of temperature on the radial compression performance of the helical stent was investigated. The findings obtained indicate that the reduction of initial pitch angle and initial diameter can enhance the radial compression performance. The reduction of initial pitch angle and the increase of initial diameter can weaken the bending stiffness of the helical stent. Moreover, the increase of temperature will reduce the radial stiffness and peak compression force of the helical stent. A favorable agreement between the theoretical and experimental results of radial compression properties was found in stents with the initial pitch angle between 14° and 21° and all initial diameters. This work can provide suggestions for the use of the theoretical formula in structure design of the helical stent.

Keywords: helical stent; mechanical properties; parameters; poly (L-lactic) acid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Lactic Acid
  • Mechanical Phenomena
  • Polyesters* / chemistry
  • Stents*

Substances

  • Polyesters
  • Lactic Acid