[Research progress on mechanism of acupuncture and moxibustion in treatment of irritable bowel syndrome]

Zhongguo Zhen Jiu. 2022 Feb 12;42(2):231-6. doi: 10.13703/j.0255-2930.20210131-0003.
[Article in Chinese]

Abstract

The current clinical evidence and underlying mechanisms of acupuncture and moxibustion in the treatment of irritable bowel syndrome (IBS) were summarized, so as to better optimize clinical treatment. The relevant articles of acupuncture and moxibustion in the treatment of IBS in recent years were retrieved and summarized. We found that the clinical efficacy of acupuncture and moxibustion in the treatment of IBS was relatively reliable. However, the mutual relationships among various mechanisms of action such as abnormal gastrointestinal motility, high visceral sensitivity, intestinal microenvironment disorders, and abnormal intestinal-brain interactions need to be further explored. The authors believe that in-depth explorations of the bidirectional regulation of "gut-brain axis", the law of changes in the abundance and diversity of intestinal flora, and the establishment of a more ideal animal model of TCM syndrome differentiation are useful ideas for subsequent research.

对当前针灸治疗肠易激综合征(IBS)的临床证据及内在机制进行总结,进而更好地优化临床治疗。检索并梳理近年来针灸治疗IBS的相关文献,发现针灸疗法的临床疗效较为明确,但其胃肠道动力异常、内脏高敏感性、肠道微环境失调和肠脑互动异常等多种作用机制间的相互关系还需进一步探讨。笔者认为深度挖掘 “肠-脑轴”的双向调节作用、肠道菌群丰富度及多样性的变化规律、建立更理想的中医辨证动物模型等是后续研究深入探讨的思路。.

Keywords: acupuncture and moxibustion; clinical evidence; irritable bowel syndrome; mechanism progress.

MeSH terms

  • Acupuncture Therapy*
  • Acupuncture*
  • Animals
  • Gastrointestinal Microbiome*
  • Irritable Bowel Syndrome* / therapy
  • Moxibustion*