A review of the pathology and treatment of TBI and PTSD

Molly Monsour; Dominique Ebedes; Cesario V Borlongan

doi:10.1016/j.expneurol.2022.114009

A review of the pathology and treatment of TBI and PTSD

Exp Neurol. 2022 May:351:114009. doi: 10.1016/j.expneurol.2022.114009. Epub 2022 Feb 9.

Authors

Molly Monsour¹, Dominique Ebedes¹, Cesario V Borlongan²

Affiliations

¹ Center of Excellence for Aging and Brain Repair, University of South Florida Morsani College of Medicine, 12901 Bruce B Downs Blvd, Tampa, FL 33612, USA.
² Center of Excellence for Aging and Brain Repair, University of South Florida Morsani College of Medicine, 12901 Bruce B Downs Blvd, Tampa, FL 33612, USA. Electronic address: cborlong@usf.edu.

PMID: 35150737
DOI: 10.1016/j.expneurol.2022.114009

Abstract

This literature review focuses on the underlying pathophysiology of TBI and PTSD symptoms, while also examining the plethora of stem cell treatment options to ameliorate these neuronal and functional changes. As more veterans return suffering from TBI and/or PTSD, it is vital that researchers discover novel therapies to mitigate the detrimental symptoms of both diagnoses. A variety of stem cell treatments have been studied and offer hopeful options for TBI and PTSD recovery.

Keywords: Neuroinflammation; Posttraumatic stress disorder; Stem cells; Traumatic brain injury.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.
Review

MeSH terms

Brain Injuries, Traumatic* / therapy
Humans
Stress Disorders, Post-Traumatic* / therapy
Veterans*