Socio-economic inequalities in cancer survival: how do they translate into Number of Life-Years Lost?

Br J Cancer. 2022 Jun;126(10):1490-1498. doi: 10.1038/s41416-022-01720-x. Epub 2022 Feb 11.

Abstract

Background: We aimed to investigate the impact of socio-economic inequalities in cancer survival in England on the Number of Life-Years Lost (NLYL) due to cancer.

Methods: We analysed 1.2 million patients diagnosed with one of the 23 most common cancers (92.3% of all incident cancers in England) between 2010 and 2014. Socio-economic deprivation of patients was based on the income domain of the English Index of Deprivation. We estimated the NLYL due to cancer within 3 years since diagnosis for each cancer and stratified by sex, age and deprivation, using a non-parametric approach. The relative survival framework enables us to disentangle death from cancer and death from other causes without the information on the cause of death.

Results: The largest socio-economic inequalities were seen mostly in adults <45 years with poor-prognosis cancers. In this age group, the most deprived patients with lung, pancreatic and oesophageal cancer lost up to 6 additional months within 3 years since diagnosis than the least deprived. For most moderate/good prognosis cancers, the socio-economic inequalities widened with age.

Conclusions: More deprived patients and particularly the young with more lethal cancers, lose systematically more life-years than the less deprived. To reduce these inequalities, cancer policies should systematically encompass the inequities component.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • England / epidemiology
  • Humans
  • Infant
  • Neoplasms* / epidemiology
  • Socioeconomic Factors