Toolboxes for plant systems biology research

Curr Opin Biotechnol. 2022 Jun:75:102692. doi: 10.1016/j.copbio.2022.102692. Epub 2022 Feb 7.

Abstract

The terms 'systems' and 'synthetic biology' are often used together, with most scientists striding between the two fields rather than adhering to a single side. Often too, scientists want to understand a system to inform the design of gene circuits that could endow it with new functions. However, this does not need to be the progression of research, as synthetic constructs can help improve our understanding of a system. Here, we review synthetic biology tool kits with the potential to overcome pleiotropic effects, compensatory mechanisms, and redundancy in plants. Combined with -omics techniques, these tools could reveal novel insights on plant growth and development, an aim that has gained renewed urgency given the impact of climate change on crop productivity.

Publication types

  • Review
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Gene Regulatory Networks
  • Plant Development
  • Plants* / genetics
  • Synthetic Biology / methods
  • Systems Biology* / methods