Current Antiretroviral Treatment Among People With Human Immunodeficiency Virus in the United States: Findings from the Centers for AIDS Research Network of Integrated Clinic Systems Cohort

Jimmy Ma; Robin M Nance; Joseph A C Delaney; Bridget M Whitney; Laura Bamford; Ronnie M Gravett; Richard D Moore; Sonia Napravnik; Kenneth H Mayer; Jeffrey M Jacobson; Katerina Christopoulos; Greer A Burkholder; Jeanne Keruly; Joseph J Eron; Jeffrey Martin; Edward R Cachay; Michael S Saag; Heidi M Crane; Mari M Kitahata

doi:10.1093/cid/ciac086

Current Antiretroviral Treatment Among People With Human Immunodeficiency Virus in the United States: Findings from the Centers for AIDS Research Network of Integrated Clinic Systems Cohort

Clin Infect Dis. 2022 Sep 10;75(4):715-718. doi: 10.1093/cid/ciac086.

Authors

Jimmy Ma¹, Robin M Nance¹, Joseph A C Delaney², Bridget M Whitney¹, Laura Bamford³, Ronnie M Gravett⁴, Richard D Moore⁵, Sonia Napravnik⁶, Kenneth H Mayer⁷, Jeffrey M Jacobson⁸, Katerina Christopoulos⁹, Greer A Burkholder⁴, Jeanne Keruly⁵, Joseph J Eron⁶, Jeffrey Martin¹⁰, Edward R Cachay³, Michael S Saag⁴, Heidi M Crane¹, Mari M Kitahata¹

Affiliations

¹ Department of Medicine, University of Washington, Seattle, Washington, USA.
² College of Pharmacy, University of Manitoba, Winnipeg, Manitoba, Canada.
³ Department of Medicine, University of California, San Diego, California, USA.
⁴ Department of Medicine, University of Alabama, Birmingham, Alabama, USA.
⁵ Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
⁶ Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
⁷ Fenway Health Institute and Harvard Medical School, Boston, Massachusetts, USA.
⁸ Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
⁹ Department of Medicine, University of California, San Francisco, California, USA.
¹⁰ Department of Epidemiology and Biostatistics, University of California, San Francisco, California, USA.

Abstract

Among 14 049 people with human immunodeficiency virus in care in 2019-2020, 96% were treated with antiretroviral therapy (ART). Current antiretroviral treatment patterns highlight high uptake of guideline-recommended ART regimens including second-generation integrase strand transfer inhibitors (dolutegravir and bictegravir) and tenofovir alafenamide, especially in antiretroviral-naive individuals initiating ART.

Keywords: ART guidelines; ART treatment trends; ART utilization; integrase inhibitor; tenofovir alafenamide.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Acquired Immunodeficiency Syndrome* / drug therapy
Alanine / therapeutic use
Anti-HIV Agents* / therapeutic use
Anti-Retroviral Agents / therapeutic use
Emtricitabine / therapeutic use
HIV
HIV Infections* / drug therapy
Heterocyclic Compounds, 3-Ring / therapeutic use
Humans
Tenofovir / therapeutic use
United States

Substances

Anti-HIV Agents
Anti-Retroviral Agents
Heterocyclic Compounds, 3-Ring
Tenofovir
Emtricitabine
Alanine

Abstract

Publication types

MeSH terms

Substances

Grants and funding