Multiregional viscoelastic properties of the porcine brain in the horizontal plane

Med Biol Eng Comput. 2022 Mar;60(3):855-862. doi: 10.1007/s11517-022-02517-z. Epub 2022 Feb 7.

Abstract

Comparison between the corpus callosum and different regions of corona radiata in the horizontal plane was tested in the article. A series of flat-punch indentation experiments were conducted on the corpus callosum and different regions of corona radiata with different loading rates on the porcine brain. A linear viscoelastic model with prony series approximation was fitted to the force-time data of all regions. The experiment data from different loading rates demonstrated that both the corona radiata and corpus callosum increased in stiffness with the increasing loading rates. The corona radiata seems to be stiffer than the corpus callosum in the horizontal plane. During the period of relaxation, statistical comparisons among the different regions showed that the posterior region of the corona radiata seems to be stiffer than the anterior and superior.

Keywords: Anisotropy; Heterogeneity; Indentation; Traumatic brain injury (TBI).

MeSH terms

  • Animals
  • Anisotropy
  • Brain*
  • Corpus Callosum
  • Swine
  • White Matter*