Association Between Preoperative Blood Glucose Level and Hospital Length of Stay in Patients With Kidney Stones Undergoing Percutaneous Nephrolithotomy

Si Sun; Weipu Mao; Shuchun Tao; Lilin Wan; Xiangyu Zou; Guangyuan Zhang; Ming Chen

doi:10.3389/fsurg.2021.820018

Association Between Preoperative Blood Glucose Level and Hospital Length of Stay in Patients With Kidney Stones Undergoing Percutaneous Nephrolithotomy

Front Surg. 2022 Jan 20:8:820018. doi: 10.3389/fsurg.2021.820018. eCollection 2021.

Authors

Si Sun¹, Weipu Mao^{1

2

3}, Shuchun Tao¹, Lilin Wan¹, Xiangyu Zou⁴, Guangyuan Zhang^{1

2}, Ming Chen^{1

2

3}

Affiliations

¹ Department of Urology, Zhongda Hospital, Southeast University, Nanjing, China.
² Surgical Research Center, Institute of Urology, Southeast University Medical School, Nanjing, China.
³ Department of Urology, Nanjing Lishui District People's Hospital, Zhongda Hospital Lishui Branch, Southeast University, Nanjing, China.
⁴ School of Basic Medical Sciences, Weifang Medical University, Weifang, China.

Abstract

Aim: To assess the effect of preoperative blood glucose (POBG) levels on the length of stay (LOS) in patients with kidney stones undergoing percutaneous nephrolithotomy (PCNL).

Methods: We conducted a retrospective study of patients who underwent PCNL at the Zhongda Hospital of Southeast University from 2013 to 2019. The relationship between POBG level and LOS was investigated by dose-response analysis curves of restricted cubic spline function.

Results: We included 310 patients and divided them into three groups (<5.04, 5.04 to <6.88, ≥6.88 mmol/L) according to the POBG levels. Patients with POBG levels ≥6.88 mmol/L (adjusted odds risk [aOR] 1.67; 95% CI 0.83-3.33) had a 67% higher risk of LOS > 2 weeks than patients with POBG levels <5.04 mmol/L. A positive dose-response analysis curve was observed between POBG and the adjusted risk of LOS >2 weeks. Similar results were observed in the subgroups analysis.

Conclusion: We demonstrated that higher POBG levels were significantly associated with longer LOS in patients with kidney stones undergoing PCNL.

Keywords: kidney stones; length of stay; percutaneous nephrolithotomy; preoperative blood glucose; retrospective study.