We report a case of a 39-year-old woman with refractory recurrent implantation failure by using endometrial receptivity analysis (ERA) test. According to a recent randomized controlled trial (RCT) study, the ERA test is expected as a helpful tool for the treatment ofinfertile patients with recurrent implantation failures. However, even in the recent RCT study, the efficacy for the ERA test for older patients (more than 38 years old) is still unclear, as the inclusion criterion for the patients in the RCT study was age 37 years or younger. In our research, the patient was 39 years old at the time of the first visit to our clinic. Therefore, the clinical utility of the ERA test may depend on the patient's age. In order to confirm the hypothesis, RCT study for older patients (more than 38 years old) should be conducted. In conclusion, our research showed the limitation of ERA test in patients with recurrent implantation failures. This will save not only our resources but also time before implying any test or investigation for the diagnosis as well management in such patients. Our research will be a good step in the management of such patients.
Keywords: age; endometrial receptivity analysis test; miscarriage; refractory recurrent implantation failure; reproductive outcomes.
Copyright © 2021, Fujishima et al.