Calcitonin-secreting pancreatic neuroendocrine tumor in a patient with elevated thyroid fine-needle aspirate calcitonin washout: A case report and review of the literature

Darryl Mason; Robert Leimbach; Robert Kitz; Robert Vietor; Nicole Vietor

doi:10.1002/ccr3.5296

Calcitonin-secreting pancreatic neuroendocrine tumor in a patient with elevated thyroid fine-needle aspirate calcitonin washout: A case report and review of the literature

Clin Case Rep. 2022 Jan 24;10(1):e05296. doi: 10.1002/ccr3.5296. eCollection 2022 Jan.

Authors

Darryl Mason¹, Robert Leimbach², Robert Kitz³, Robert Vietor¹, Nicole Vietor²

Affiliations

¹ F. Edward Hebert School of Medicine Uniformed Services University Bethesda Maryland USA.
² Department of Endocrinology Walter Reed National Military Medical Center Bethesda Maryland USA.
³ Department of Pathology Walter Reed National Military Medical Center Bethesda Maryland USA.

Abstract

We report the unique case of a patient with previously proven non-functional PanNET and Graves' disease with thyroid nodules. The patient had elevated intranodular calcitonin, but no MTC or c-cell hyperplasia on thyroidectomy. They were found to have calcitonin secreting PanNET. This case presents a false-positive intranodular calcitonin.

Keywords: calcitonin; calcitonin wash; medullary thyroid cancer; pancreatic neuroendocrine tumor.

Publication types

Case Reports