DdCBE-mediated mitochondrial base editing in human 3PN embryos

Cell Discov. 2022 Feb 1;8(1):8. doi: 10.1038/s41421-021-00358-y.

Xiaoxu Chen^#¹, Dong Liang^#², Jiayin Guo^#^{1

3}, Junqiang Zhang^#⁴, Haifeng Sun^#¹, Xiaolan Zhang⁴, Jiachuan Jin¹, Yichen Dai¹, Qinmin Bao², Xuezhen Qian¹, Lei Tan¹, Ping Hu², Xiufeng Ling⁵, Bin Shen^{6

7

8

9}, Zhengfeng Xu¹⁰

¹ State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China.
² Department of Prenatal Diagnosis, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, Jiangsu, China.
³ Gusu School, Nanjing Medical University, Nanjing, Jiangsu, China.
⁴ Department of Reproduction, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, Jiangsu, China.
⁵ Department of Reproduction, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, Jiangsu, China. lingxiufeng_njfy@163.com.
⁶ State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China. binshen@njmu.edu.cn.
⁷ Department of Prenatal Diagnosis, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, Jiangsu, China. binshen@njmu.edu.cn.
⁸ Gusu School, Nanjing Medical University, Nanjing, Jiangsu, China. binshen@njmu.edu.cn.
⁹ Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China. binshen@njmu.edu.cn.
¹⁰ Department of Prenatal Diagnosis, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, Jiangsu, China. zhengfeng_xu_nj@163.com.

^# Contributed equally.

No abstract available

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