Case Report: Combination of Pressure Guidewire and Optical Coherence Tomography-Guided Drug-Coated Balloon Revascularization for Renal Artery Fibromuscular Dysplasia

Yuxi Li; Xinyan Wen; Bo Zheng; Ming Chen; Wei Ma; Jianping Li

doi:10.3389/fcvm.2021.773563

Case Report: Combination of Pressure Guidewire and Optical Coherence Tomography-Guided Drug-Coated Balloon Revascularization for Renal Artery Fibromuscular Dysplasia

Front Cardiovasc Med. 2022 Jan 13:8:773563. doi: 10.3389/fcvm.2021.773563. eCollection 2021.

Authors

Yuxi Li^{1

2

3}, Xinyan Wen^{1

2

3}, Bo Zheng^{1

2

3}, Ming Chen^{1

2

3}, Wei Ma^{1

2

3}, Jianping Li^{1

2

3}

Affiliations

¹ Department of Cardiology, Peking University First Hospital, Beijing, China.
² Institute of Cardiovascular Disease, Peking University First Hospital, Beijing, China.
³ Hypertension Precision Diagnosis and Treatment Research Center, Peking University First Hospital, Beijing, China.

Abstract

Fibromuscular dysplasia (FMD) is the second common cause of renovascular hypertension. With the advent of endovascular therapy, angiography has become a diagnostic gold standard for FMD. Optical coherence tomography (OCT) by reflecting in vivo histology may improve diagnostic and classification accuracy. Renal fractional flow reserve (rFFR), measured by pressure guidewire, may distinguish the patients who may benefit from revascularization by identifying physiologically significant stenoses. However, the role of usage of both OCT and rFFR is not well-studied. We herein report a 17-year-old male with renovascular hypertension due to FMD. Angioplasty of drug-coated balloon (DCB) guided by OCT and FFR favorably achieved blood pressure (BP) control. In conclusion, the utility of both OCT and FFR may be useful for the appropriate selection of patients with renal FMD.

Keywords: drug-coated balloon; fibromuscular dysplasia; optical coherence tomography; pressure guidewire; secondary hypertension.

Publication types

Case Reports