Functional Magnetic Resonance Imaging Study of Electroacupuncture Stimulating Uterine Acupoints

Comput Math Methods Med. 2022 Jan 19:2022:4295985. doi: 10.1155/2022/4295985. eCollection 2022.

Abstract

Objective: Based on resting-state functional magnetic resonance imaging (rs-fMRI), to observe the changes of brain function of bilateral uterine points stimulated by electroacupuncture, so as to provide imaging basis for acupuncture in the treatment of gynecological and reproductive diseases.

Methods: 20 healthy female subjects were selected to stimulate bilateral uterine points (EX-CA1) by electroacupuncture. FMRI data before and after acupuncture were collected. The ReHo values before and after acupuncture were compared by using the analysis method of regional homogeneity (ReHo) of the whole brain, so as to explore the regulatory effect of acupuncture intervention on brain functional activities of healthy subjects.

Results: Compared with before acupuncture, the ReHo values of the left precuneus lobe, left central posterior gyrus, calcarine, left lingual gyrus, and cerebellum decreased significantly after acupuncture.

Conclusion: Electroacupuncture at bilateral uterine points can induce functional activities in brain areas such as the precuneus, cerebellum, posterior central gyrus, talform sulcus, and lingual gyrus. The neural activities in these brain areas may be related to reproductive hormone level, emotional changes, somatic sensation, and visual information. It can clarify the neural mechanism of acupuncture at uterine points in the treatment of reproductive and gynecological diseases to a certain extent.

MeSH terms

  • Acupuncture Points*
  • Adult
  • Brain / physiology
  • Brain Mapping
  • Computational Biology
  • Electroacupuncture / methods*
  • Female
  • Functional Neuroimaging / methods
  • Functional Neuroimaging / statistics & numerical data
  • Genital Diseases, Female / diagnostic imaging
  • Genital Diseases, Female / physiopathology
  • Healthy Volunteers
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Magnetic Resonance Imaging / statistics & numerical data
  • Uterus / diagnostic imaging*
  • Uterus / physiology
  • Young Adult