Broad Spectrum Algae Compounds Against Viruses

Jacqueline Graff Reis; Rafael Dorighello Cadamuro; Ariadne Cristiane Cabral; Izabella Thaís da Silva; David Rodríguez-Lázaro; Gislaine Fongaro

doi:10.3389/fmicb.2021.809296

Broad Spectrum Algae Compounds Against Viruses

Front Microbiol. 2022 Jan 14:12:809296. doi: 10.3389/fmicb.2021.809296. eCollection 2021.

Authors

Jacqueline Graff Reis¹, Rafael Dorighello Cadamuro¹, Ariadne Cristiane Cabral^{1

2}, Izabella Thaís da Silva^{1

3}, David Rodríguez-Lázaro^{4

5}, Gislaine Fongaro¹

Affiliations

¹ Laboratory of Applied Virology, Department of Microbiology, Immunology, and Parasitology, Federal University of Santa Catarina, Florianópolis, Brazil.
² Department of Dentistry, Federal University of Santa Catarina, Florianópolis, Brazil.
³ Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Florianópolis, Brazil.
⁴ Microbiology Division, Faculty of Sciences, University of Burgos, Burgos, Spain.
⁵ Research Centre for Emerging Pathogens and Global Health, University of Burgos, Burgos, Spain.

Abstract

The pharmaceutical industry is currently trying to develop new bioactive compounds to inactivate both enveloped and non-enveloped viruses for therapeutic purposes. Consequently, microalgal and macroalgal bioactive compounds are being explored by pharmaceutical, as well as biotechnology and food industries. In this review, we show how compounds produced by algae include important candidates for viral control applications. We discuss their mechanisms of action and activity against enveloped and non-enveloped viruses, including those causing infections by enteric, parenteral, and respiratory routes. Indeed, algal products have potential in human and animal medicine.

Keywords: algae; antiviral; health; mechanisms; virucidal.

Publication types

Review