A feasibility study on low-dose mindfulness-based stress reduction intervention among prediabetes and diabetes patients

Tong Xia; Snehal Lopes; Liwei Chen; Rebecca Roth; Heidi Zinzow; Karyn Jones; Lingling Zhang; Lu Shi; Meenu Jindal

doi:10.1016/j.ctim.2022.102810

A feasibility study on low-dose mindfulness-based stress reduction intervention among prediabetes and diabetes patients

Complement Ther Med. 2022 May:65:102810. doi: 10.1016/j.ctim.2022.102810. Epub 2022 Jan 29.

Authors

Tong Xia¹, Snehal Lopes², Liwei Chen³, Rebecca Roth⁴, Heidi Zinzow⁵, Karyn Jones⁶, Lingling Zhang⁷, Lu Shi⁸, Meenu Jindal⁹

Affiliations

¹ Department of Epidemiology, University of California Los Angeles, Los Angeles, CA 90095, USA. Electronic address: xiatong@g.ucla.edu.
² Department of Public Health Sciences, Clemson University, 500 Edwards Hall, Clemson, SC 29634, USA. Electronic address: snehall@g.clemson.edu.
³ Department of Epidemiology, University of California Los Angeles, Los Angeles, CA 90095, USA. Electronic address: cliwei86@ucla.edu.
⁴ Department of Public Health Sciences, Clemson University, 500 Edwards Hall, Clemson, SC 29634, USA. Electronic address: raroth@g.clemson.edu.
⁵ Department of Psychology, Clemson University, Clemson, SC 29634, USA. Electronic address: hzinzow@clemson.edu.
⁶ School of Nursing, Clemson University, Edwards Hall, Clemson, SC 29634, USA. Electronic address: karynj@clemson.edu.
⁷ College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA 02125, USA. Electronic address: Lingling.Zhang@umb.edu.
⁸ Department of Public Health Sciences, Clemson University, 500 Edwards Hall, Clemson, SC 29634, USA. Electronic address: lus@clemson.edu.
⁹ Department of Internal Medicine, Prisma Health, 701 Grove Road, Greenville, SC 29605, USA. Electronic address: meenu.jindal@prismahealth.org.

PMID: 35093511
DOI: 10.1016/j.ctim.2022.102810

Abstract

Objectives: To investigate the feasibility of delivering a low-dose mindfulness-based stress reduction (MBSR) intervention among prediabetes/diabetes patients in a clinical setting.

Design and setting: This was a single-arm, mixed methods, feasibility study among prediabetes/diabetes patients at a healthcare center in United States.

Intervention: The low-dose MBSR intervention was delivered in group format over 4 waves and each wave comprised 8-10 h of 8 sessions over 6-8 weeks.

Main outcome measures: We evaluated recruitment, adherence, and attrition rates, participants' satisfaction, motivation and barriers of low-dose MBSR. Psychological, behavioral, and physical measures were compared between pre- and post-intervention.

Results: We enrolled 19 participants of 34 eligible individuals with a recruitment rate of 55.9%. Among 19 enrolled participants, 4 dropped out after baseline data collection and did not attend any session and 1 attended one session but did not finish post-intervention data collection, resulting in an attrition rate of 26.3%. Among 15 participants attending at least one session, 46.7% attended all sessions and 80.0% attended at least 5 sessions. Qualitative analysis among 11 participants indicated that 90.9% had positive overall experience with the intervention. Compared to pre-intervention, there was a significant reduction in depression score (mean reduction = 5.04, SD = 7.66, p = 0.02), a higher proportion of engaging in flexibility exercises (42.86% vs. 85.71%, p = 0.01) and a lower level of glycosylated hemoglobin (HbA1c) (mean reduction = 1.43%, SD = 2.54%, p = 0.03) at post-intervention.

Conclusions: Delivering a low-dose MBSR intervention to prediabetes/diabetes patients in a primary care setting is feasible. Future studies with randomized controlled design and larger sample are warranted.

Keywords: Diabetes; Feasibility; Low-dose mindfulness intervention.

MeSH terms

Feasibility Studies
Glycated Hemoglobin
Humans
Mindfulness* / methods
Prediabetic State* / therapy
Stress, Psychological / therapy

Substances

Glycated Hemoglobin A