A rhodamine derivative probe for highly selective detection of Cu(II)

Liming Hu; Yifan Lin; Peng Wang; Hongsheng Zhang; Minyao Liu; Shanyan Mo

doi:10.31083/j.fbl2701028

A rhodamine derivative probe for highly selective detection of Cu(II)

Front Biosci (Landmark Ed). 2022 Jan 18;27(1):28. doi: 10.31083/j.fbl2701028.

Authors

Liming Hu¹, Yifan Lin¹, Peng Wang¹, Hongsheng Zhang¹, Minyao Liu¹, Shanyan Mo¹

Affiliation

¹ College of Life Science and Chemistry, Beijing Key Laboratory of Environmental and Oncology, Faculty of Environment and Life, Beijing University of Technology, 100124 Beijing, China.

PMID: 35090333
DOI: 10.31083/j.fbl2701028

Abstract

Background: Abnormal Cu(II) ions levels may affect many biological functions, and it is of great importance to detect Cu(II) ions in organisms.

Methods: Herein, we report a near-infrared (NIR) fluorescent probe EtRh-N-NH₂ for the detection of Cu(II). In the probe structure, a rhodamine core was used, and a hydrazine group was employed as the responsive site. Results & Conlusions: EtRh-N-NH₂ displayed sensitive, specific and fast response upon Cu(II) with excellent linear relationship between the concentration and fluorescence emission intensity in 0-1 μM range. The releasing EtRh-COOH exhibited 762 nm of emission wavelength with a 75 nm of Stokes shift.

Keywords: Cu(II) detection; Fluorescent probe; Large Stokes shift.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Fluorescent Dyes* / chemistry
Rhodamines / chemistry

Substances

Fluorescent Dyes
Rhodamines