Tcof1 haploinsufficiency promotes early T cell precursor-like leukemia in NrasQ61R/+ mice

Leukemia. 2022 Apr;36(4):1167-1170. doi: 10.1038/s41375-022-01510-7. Epub 2022 Jan 26.
No abstract available

MeSH terms

  • Animals
  • GTP Phosphohydrolases
  • Haploinsufficiency / genetics
  • Intracellular Signaling Peptides and Proteins* / genetics
  • Leukemia* / genetics
  • Membrane Proteins
  • Mice
  • Monomeric GTP-Binding Proteins* / genetics
  • Mutation
  • Nuclear Proteins
  • Phosphoproteins* / genetics
  • Precursor Cells, T-Lymphoid*

Substances

  • Intracellular Signaling Peptides and Proteins
  • Membrane Proteins
  • Nuclear Proteins
  • Phosphoproteins
  • Tcof1 protein, mouse
  • GTP Phosphohydrolases
  • Monomeric GTP-Binding Proteins
  • Nras protein, mouse