The novel allele HLA-DQA1*05:05:10 was detected in a Nigerian who also lacks the DRB5 gene in the DRB1*16 haplotype

HLA. 2022 Jun;99(6):667-668. doi: 10.1111/tan.14563. Epub 2022 Feb 9.

Abstract

One synonymous nucleotide substitution in exon 2 of DQA1*05:05:01:13 results in a novel allele, HLA-DQA1*05:05:10.

Keywords: DR51 absent; HLA-DQA1; HLA-DR16; next generation sequencing.

Publication types

  • Case Reports

MeSH terms

  • Alleles
  • HLA-DQ alpha-Chains / genetics
  • HLA-DQ beta-Chains / genetics
  • HLA-DRB1 Chains / genetics
  • Haplotypes*
  • Humans
  • Nigeria

Substances

  • HLA-DQ alpha-Chains
  • HLA-DQ beta-Chains
  • HLA-DQA1 antigen
  • HLA-DRB1 Chains