T and NK Cell-Based Immunotherapy in Chronic Viral Hepatitis and Hepatocellular Carcinoma

Cells. 2022 Jan 6;11(2):180. doi: 10.3390/cells11020180.

Abstract

In chronic viral hepatitis and in hepatocarcinoma (HCC), antigen-specific T cells are deeply exhausted, and evidence of dysfunction has also been observed for NK cells, which can play a pathogenetic role, exerting a regulatory activity on adaptive immune responses [...].

Publication types

  • Editorial
  • Introductory Journal Article

MeSH terms

  • Carcinoma, Hepatocellular / immunology*
  • Carcinoma, Hepatocellular / therapy*
  • Chronic Disease
  • Cytokines / metabolism
  • Hepatitis, Viral, Human / immunology*
  • Hepatitis, Viral, Human / therapy*
  • Humans
  • Immunotherapy*
  • Killer Cells, Natural / immunology*
  • Liver Neoplasms / immunology
  • Liver Neoplasms / therapy*
  • Lymphocytes, Tumor-Infiltrating / immunology
  • T-Lymphocytes / immunology*

Substances

  • Cytokines