Relentless Hypoxia in a Patient With Carcinoid Syndrome

Cureus. 2021 Dec 18;13(12):e20497. doi: 10.7759/cureus.20497. eCollection 2021 Dec.

Abstract

Patent foramen ovale (PFO) in patients with carcinoid heart disease (CHD) may result in hypoxia due to the presence of large right (R) to left (L) intracardiac shunts leading to hypoxia and worsening clinical condition. Percutaneous closure of the PFO can normalize oxygen saturation, relieve symptoms, and lessens left-sided heart valves involvement. We describe a case of a 70-year-old female patient with a history of small bowel neuroendocrine tumor on monthly octreotide infusion presented with worsening exertional dyspnea and hypoxia secondary to R to L intracardiac shunt through the PFO. The decision was made to close the PFO percutaneously with Amplatzer (Plymouth, MN: Abbott) PFO occluder device which resulted in immediate normalization of oxygen saturation and relief of her dyspnea.

Keywords: carcinoid heart disease; carcinoid tumour; hypoxia; patent foramen ovale; percutaneous closure; right to left shunting; valvular heart disease.

Publication types

  • Case Reports