Cerebral venous sinus thrombosis in infant with COVID-19

Acta Neurochir (Wien). 2022 Mar;164(3):853-858. doi: 10.1007/s00701-022-05116-x. Epub 2022 Jan 19.

Abstract

We present a rare case of cerebral venous sinus thrombosis in a COVID-19-positive, 2-month-old infant, to this day the youngest described patient with this rare combination of findings. He was hospitalized with focal seizures. The first brain imaging showed subdural hematoma and focal ischemic changes. The subdural hematoma was successfully evacuated. The control imaging, done due to lethargy, showed an extensive cerebral venous sinus thrombosis. The thrombosis was managed with low molecular weight heparin leading to clinical and radiological improvement. With this case report, we would like to add to the information pool of COVID-19 neurological manifestations in children, particularly those younger than 1 year.

Keywords: COVID-19; Case report; Cerebral venous sinus thrombosis; Infant.

Publication types

  • Case Reports

MeSH terms

  • COVID-19* / complications
  • Child
  • Cranial Sinuses / diagnostic imaging
  • Hematoma, Subdural
  • Humans
  • Infant
  • Male
  • SARS-CoV-2
  • Sinus Thrombosis, Intracranial* / diagnostic imaging
  • Sinus Thrombosis, Intracranial* / etiology