Paper based micro/nanofluidics devices for biomedical applications

Prog Mol Biol Transl Sci. 2022;186(1):159-190. doi: 10.1016/bs.pmbts.2021.07.011. Epub 2021 Aug 19.

Abstract

This chapter details the significance, fabrication and biomedical applications of paper-based microfluidic devices. The first part of the chapter describes the importance of paper diagnostic devices, highlighting pretreatment, dipsticks, lateral flow assays, and microPADs. Various methods followed for the fabrication of the paper analytical devices are discussed in the second part. The last part is about some of the important biomedical applications of paper analytical devices. Finally, the challenges and research gaps in the paper microfluidics for biomedical applications are presented.

Keywords: Clinical diagnosis; Dipsticks; Lateral flow assay; MicroPADs; Paper-based analytical devices.

MeSH terms

  • Humans
  • Lab-On-A-Chip Devices
  • Microfluidic Analytical Techniques*
  • Microfluidics