An introduction to microfluidics and their applications

Prog Mol Biol Transl Sci. 2022;186(1):1-14. doi: 10.1016/bs.pmbts.2021.07.006. Epub 2021 Aug 3.

Abstract

In the past decade, microfluidics and lab-on-chip are rapidly growing area. It has been used for number of biology to biotechnology and medicine applications. It has the potential to reduce cost of reagent and time of experiment. It has been used integrated with automation for extraction and detection of protein, nucleic acids, enzymes, metabolites and delivery of drug to target location. It has been used for drug discovery, high throughput screening of potent drug and used for delivery. Paper based microfluidics was used for point-of-care diagnosis for accurate treatment of diseases. In this chapter, we highlight advances of microfluidics devices for number of biological and translational science applications.

Keywords: DNA; Devices; Drug discovery; High-throughput; Microfluidics; PDMS; Paper; RNA.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Automation
  • High-Throughput Screening Assays
  • Humans
  • Lab-On-A-Chip Devices
  • Microfluidics*
  • Translational Science, Biomedical*