The active mode-locking (AML) technique has been widely used in erbium-doped fiber lasers to generate picosecond pulse trains. Here we propose a novel active mode-locking dual-loop optoelectronic oscillator (AML-DL-OEO), which can generate microwave frequency comb (MFC) signals with adjustable comb spacings. Based on this scheme, the order of harmonic mode-locking is dramatically decreased for a certain AML driving frequency compared with a single-loop AML-OEO. Thus, the supermode noise caused by harmonic mode-locking can be efficiently suppressed. In addition, the sidemodes are well suppressed by the dual-loop architecture. An experiment is performed. MFC signals with different comb spacings are generated under fundamental or harmonic mode-locking states. AML-DL-OEO systems with different length differences between two loops are implemented to evaluate supermode noise suppression capability. The performance of the generated MFC signals is recorded and analyzed.