Microdialysis techniques and microdialysis-based patient-near diagnostics

Anal Bioanal Chem. 2022 Apr;414(10):3165-3175. doi: 10.1007/s00216-021-03830-6. Epub 2022 Jan 14.

Abstract

This article will debate the usefulness of POCT measurements and the contribution microdialysis can make to generating valuable information. A particular theme will be the rarely considered difference between ex vivo sampling, which typically generates only a static measure of concentration, and in vivo measurements that are subject to dynamic changes due to mass transfer. Those dynamic changes provide information about the patients' physiological state.

Keywords: Microdialysis; Point-of-care testing; Sensors.

Publication types

  • Review

MeSH terms

  • Humans
  • Microdialysis* / methods