Failure to Achieve Target Drug Concentrations During Induction and Not HLA-DQA1∗05 Carriage Is Associated With Antidrug Antibody Formation in Patients With Inflammatory Bowel Disease

Gastroenterology. 2022 May;162(6):1746-1748.e3. doi: 10.1053/j.gastro.2022.01.009. Epub 2022 Jan 11.

Authors

Elizabeth A Spencer¹, Jordan Stachelski², Thierry Dervieux², Marla C Dubinsky³

Affiliations

¹ Department of Pediatrics, Division of Pediatric Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: elizabeth.spencer@mssm.edu.
² Prometheus Laboratories Inc, San Diego, California.
³ Department of Pediatrics, Division of Pediatric Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York.

PMID: 35026235
DOI: 10.1053/j.gastro.2022.01.009

No abstract available

MeSH terms

Alleles
Antibody Formation*
Gene Frequency
Genetic Predisposition to Disease
HLA-DQ alpha-Chains / genetics
Humans
Inflammatory Bowel Diseases* / drug therapy

Substances

HLA-DQ alpha-Chains