Chlorhexidine skin cleaning to reduce clean-catch urine contamination in infants: A pilot study

Emerg Med Australas. 2022 Apr;34(2):282-284. doi: 10.1111/1742-6723.13913. Epub 2022 Jan 12.

Abstract

Objective: Clean-catch urine (CCU) samples are frequently contaminated. Our aim was to determine if cleaning with 0.1% chlorhexidine before CCU is a safe and feasible method to reduce contamination.

Methods: Prospective interventional pilot study. Children 1-24 months underwent perigenital skin cleaning with 0.1% chlorhexidine. Primary outcome was contamination rate, and secondary outcomes were parent and clinician satisfaction with the procedure.

Results: Twelve of 54 urine samples were contaminated (22%, 95% CI 13-35). Over 90% of parents and clinicians were either 'satisfied' or 'very satisfied'. No adverse events were recorded.

Conclusion: Cleaning with chlorhexidine solution before CCU is safe and feasible.

Keywords: clean-catch urine collection; contamination; paediatric emergency medicine; paediatrics; urinary tract infection.

MeSH terms

  • Child
  • Chlorhexidine* / pharmacology
  • Chlorhexidine* / therapeutic use
  • Humans
  • Infant
  • Pilot Projects
  • Prospective Studies
  • Urinary Tract Infections*
  • Urine Specimen Collection / methods

Substances

  • Chlorhexidine