Advances in Portable Visual Detection of Pathogenic Bacteria

ACS Appl Bio Mater. 2020 Nov 16;3(11):7291-7305. doi: 10.1021/acsabm.0c00984. Epub 2020 Oct 23.

Abstract

Food safety and regulation of consumer welfare are of great concern, so it is necessary to be able to detect pathogenic bacteria quickly and effectively. Although traditional methods of pathogen detection are reliable and widely used, the detection and analysis processes are cumbersome and time-consuming, which is not conducive to fast assays in the field. New detection strategies have emerged in recent years, especially point-of-care testing (POCT) methods, which do not rely on the laboratory and have become an important development direction for pathogen detection. Many visual detection schemes have been developed that integrate portable glucose meters (PGMs), test strips, smartphones, and other portable devices. Importantly, portable and ultrasensitive biosensors have vast promise in detecting pathogens, as they can be suitable tools for clinical diagnosis and the regulation of food safety. This Review focuses on the latest advances in portable device-based methods for visual detection of pathogens, evaluating their advantages and disadvantages.

Keywords: clinical diagnosis; food safety; pathogenic bacteria; point-of-care testing; portable devices; visual detection.