Clinicopathological Correlation of Pulp Stones and Its Association with Hypertension and Hyperlipidemia: An Hospital-based Prevalence Study

J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S1268-S1274. doi: 10.4103/jpbs.jpbs_475_21. Epub 2021 Nov 10.

Abstract

Introduction: Pulp stones are the discrete calcification, located in pulp tissue or attached to or embedded in dentin. It occurs in physiological and pathological conditions. The exact etiopathogenesis of various types of pulp calcifications is unknown and the prevalence varies from 8% to 90%. The histopathological identification of pulp stones is higher than the radiological identification.

Objective: The aim of the study is to evaluate and correlate the clinical parameters and histopathological analysis of pulp stone with systemic hypertension and hyperlipidemia.

Materials and methods: Seventy patients were selected for the study and a detailed case history was recorded. The radiological investigations were noted down and extirpated pulp tissues were sent for processing. The results were analyzed statistically using Chi-square test.

Results: Out of 70 patients studied, pulp stones were observed radiologically in 14 patients and histopathologically in 30 patients. The presence of irregular and nonlaminated type of pulp stones histopathologically was significantly correlated with hypertension and hyperlipidemia.

Conclusion: The patients with the histopathological presence of nonlaminated and irregular-shaped pulp should be evaluated for lipid profile and hypertension.

Keywords: Cardiovascular disease; hyperlipidemia; hypertension; pulp stones.