COVID-19 infection and its consequences among surgical oncology patients: A systematic analysis, meta-analysis and meta-regression

J Surg Oncol. 2022 Apr;125(5):813-823. doi: 10.1002/jso.26787. Epub 2022 Jan 11.

Abstract

We conducted this meta-analysis to address the outcomes in cancer patients after oncologic surgery during COVID-19 pandemic. The primary endpoint was the COVID-19-related mortality rate. Higher body mass index was significantly and negatively associated with higher all-cause mortality and in-hospital COVID-19 infection rates. Male sex, preoperative respiratory disease, and smoking history were positively and significantly associated with increased all-cause mortality rates. Furthermore, male sex was positively and significantly associated with the COVID-19 infection rate.

Keywords: COVID-19; cancer; meta-analysis; mortality; surgery.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • COVID-19* / complications
  • Humans
  • Male
  • Medical Oncology
  • Neoplasms* / complications
  • Neoplasms* / mortality
  • Pandemics
  • Risk Factors
  • SARS-CoV-2
  • Sex Factors
  • Smoking / adverse effects