Mothers in Need of Lactation Support May Benefit from Early Postnatal Galactagogue Administration: Experience from a Single Center

Nutrients. 2021 Dec 29;14(1):140. doi: 10.3390/nu14010140.

Abstract

Background: Galactagogues are substances that promote lactation, although data on their effects on humans remain limited. We investigated the efficacy of Silitidil to increase milk supply and duration of breastfeeding of a specific subgroup of mothers in need of lactation support.

Methods: 161 mothers from November 2018 until January 2021 were the study subjects in this retrospective study; during their hospitalization, due to neonatal or maternal factors that inhibited lactation, they were prescribed galactagogues. Mothers were surveyed by telephone interview via a 13-item questionnaire.

Results: 73.91%, were primigravidas, 78.26% gave birth by cesarean section (CS) and 72.05% continued to take galactagogues after hospital discharge. Of the neonates, 24.22% were preterm ≤37 weeks of gestation, and 55.9% had birth weight (BW) between 2500 and 3500 g. With respect to breastfeeding rates, 100% were breastfed during their first week, 98.8% breastfed during the first month, 87% during the first 4 months, dropping to 56.5% at 6 months, 41% at 1 year and 19.3% over 1 year of age.

Conclusions: This study demonstrates that administration of a galactagogue containing Silitidil (Piulatte-Humana) improves breastfeeding rates at from 1 until 12 months of life in mothers with low milk supply during their hospital stay. Further studies are needed to generate evidence-based strategies to improve breastfeeding outcomes.

Keywords: Silitidil; breastfeeding; breastfeeding rates; galactagogues; lactation; neonate.

MeSH terms

  • Adult
  • Breast Feeding*
  • Female
  • Galactogogues / administration & dosage*
  • Galactogogues / pharmacology
  • Humans
  • Infant
  • Infant, Newborn
  • Lactation / drug effects*
  • Male
  • Maternal Nutritional Physiological Phenomena / physiology*
  • Postnatal Care*
  • Retrospective Studies
  • Surveys and Questionnaires
  • Time Factors
  • Young Adult

Substances

  • Galactogogues