Pruritus as a Presenting Symptom of FIP1L1-PDGFRA-Positive Chronic Eosinophilic Leukemia

Mohammad Abu-Tineh; Esra'a Aljaloudi; Mohamed A Yassin

doi:10.2147/JBM.S319441

Pruritus as a Presenting Symptom of FIP1L1-PDGFRA-Positive Chronic Eosinophilic Leukemia

J Blood Med. 2021 Dec 29:12:1061-1063. doi: 10.2147/JBM.S319441. eCollection 2021.

Authors

Mohammad Abu-Tineh¹, Esra'a Aljaloudi², Mohamed A Yassin¹

Affiliations

¹ Department of Oncology- Hematology and BMT Section, National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar.
² Department of Family Medicine, Hamad Medical Corporation, Doha, Qatar.

Abstract

Eosinophilia can be found in a variety of benign and malignant conditions, and a persistent eosinophilic count of more than 1500/mm³ necessitates additional investigation. Patients with FIP1L1-PDGFRA-positive chronic eosinophilic leukemia might present as asymptomatic or in a catastrophic state with multi-organ involvement. We present the case of a young male patient who was diagnosed with FIP1L1-PDGFRA chronic eosinophilic leukemia after a long history of recurrent cutaneous symptoms with no systemic signs.

Keywords: FIP1L1-PDGFRA; chronic eosinophilic leukemia; eosinophilia; imatinib.

Publication types

Case Reports