Hyperprogressive Disease After Pembrolizumab Treatment in Advanced Epstein-Barr Virus-Associated Gastric Adenocarcinoma With ERBB2 Amplification

JCO Precis Oncol. 2021 Nov:5:370-377. doi: 10.1200/PO.20.00272.
No abstract available

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenocarcinoma / complications
  • Adenocarcinoma / diagnostic imaging
  • Adenocarcinoma / drug therapy*
  • Adenocarcinoma / pathology
  • Aged
  • Antibodies, Monoclonal, Humanized / therapeutic use*
  • Epstein-Barr Virus Infections / complications
  • Humans
  • Immune Checkpoint Inhibitors / therapeutic use*
  • Male
  • Positron Emission Tomography Computed Tomography
  • Receptor, ErbB-2 / metabolism*
  • Stomach Neoplasms / complications
  • Stomach Neoplasms / diagnostic imaging
  • Stomach Neoplasms / drug therapy*
  • Stomach Neoplasms / pathology
  • Tomography, X-Ray Computed

Substances

  • Antibodies, Monoclonal, Humanized
  • Immune Checkpoint Inhibitors
  • pembrolizumab
  • ERBB2 protein, human
  • Receptor, ErbB-2