Short term exposure to ambient air pollutants and cardiovascular emergency department visits in Mexico city

Abstract

Available data on the acute cardiovascular effect of ambient air pollution (AAP) in Latin America is limited considering that over 80% of its 1 billion inhabitants live in urban settlements with poor air quality. The study aim was to evaluate the association between Cardiovascular Emergency Department Visits (CEDVs) and AAP in Mexico City from 2016 to 2019 using generalized additive models with distributed lags to examine the percentage change of CEDVs and a backward approach of time-series model to calculate attributable fractions. A total of 48,891 CEDVs were recorded in a period of 1019 days. We estimated a significant percentage increase for each 10 μg/m³ of PM₁₀ at Lag0-5 (2.8%, 95%CI 0.6-5.0), PM_2.5 at Lag0-6 (3.7%, 95%CI 0.1-7.6), O₃ at Lag0-5 (1.1%, 95%CI 0.2-2.0), NO₂ at Lag0-4 (2.5%, 95%CI 0.3-4.7) and for each 1 mg/m³ of CO at Lag0 (6.6%, 95%CI 0.3-13.2). Overall, 10.3% of CEDVs in Mexico City may be related to PM¹⁰ exposure, 9.5% to PM_2.5, 10.3% to O₃, 11% to NO₂ and 5.7% to CO. AAP significantly increase cardiovascular morbidity impacting on emergency medical services.

Keywords: Air pollution; Cardiovascular disease; Emergency department visits; Latin America; Short-term exposure; Time-series.