Cardiac considerations in liver transplantation

Vikram Sharma; Cerise Kleb; Chirag Sheth; Beni Rai Verma; Vardhmaan Jain; Ruchi Sharma; Parth Parikh; Jacek Cywinski; K V Narayanan Menon; Jamak Modaresi Esfeh; Bijan Eghtesad; Cristiano Quintini; Teresa Diago Uso; Michael Z Y Tong; Ravi Nair; Ajay Bhargava; Maan Fares

doi:10.3949/ccjm.89a.21006

Cardiac considerations in liver transplantation

Cleve Clin J Med. 2022 Jan 4;89(1):46-55. doi: 10.3949/ccjm.89a.21006.

Authors

Vikram Sharma¹, Cerise Kleb², Chirag Sheth³, Beni Rai Verma⁴, Vardhmaan Jain², Ruchi Sharma⁵, Parth Parikh⁶, Jacek Cywinski⁷, K V Narayanan Menon⁸, Jamak Modaresi Esfeh⁹, Bijan Eghtesad¹⁰, Cristiano Quintini¹¹, Teresa Diago Uso¹², Michael Z Y Tong¹³, Ravi Nair¹⁴, Ajay Bhargava¹⁵, Maan Fares¹⁶

Affiliations

¹ Department of Hospital Medicine, Cleveland Clinic, Cleveland, OH; Department of Cardiovascular Medicine, University of Iowa, Iowa City.
² Department of Internal Medicine, Cleveland Clinic, Cleveland, OH.
³ Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, OH.
⁴ Department of Hospital Medicine, Cleveland Clinic; Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
⁵ Department of Hospital Medicine, Cleveland Clinic, Cleveland, OH.
⁶ Heart, Vascular, and Thoracic Institute, Cleveland Clinic; Clinical Instructor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
⁷ Department of General Anaesthesia, Cleveland Clinic; Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
⁸ Medical Director of Liver Transplantation, Digestive Disease and Surgery Institute, Cleveland Clinic; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
⁹ Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH.
¹⁰ Digestive Disease and Surgery Institute, Cleveland Clinic; Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
¹¹ Digestive Disease and Surgery Institute, Cleveland Clinic; Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
¹² Digestive Disease and Surgery Institute, Cleveland Clinic; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
¹³ Heart, Vascular, and Thoracic Institute, Cleveland Clinic; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
¹⁴ Heart, Vascular, and Thoracic Institute, Cleveland Clinic; Professor Emeritus, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
¹⁵ Heart, Vascular, and Thoracic Institute, Cleveland Clinic; Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
¹⁶ Heart, Vascular, and Thoracic Institute, Cleveland Clinic; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH faresm@ccf.org.

PMID: 34983801
DOI: 10.3949/ccjm.89a.21006

Abstract

Cardiovascular events have a major impact on overall outcomes after liver transplantation. Today's transplant patients are older than those in the past and therefore are more likely to have coexisting cardiac comorbidities. In addition, pathophysiologic effects of advanced liver disease on the circulatory system pose challenges in perioperative management. This review discusses important preoperative, intraoperative, and postoperative cardiac considerations in patients undergoing liver transplant.

Publication types

Review

MeSH terms

Heart
Humans
Liver Diseases*
Liver Transplantation*
Postoperative Complications
Postoperative Period