Outcomes of Early Versus Delayed Completion Thyroidectomy for Malignancy

Am Surg. 2023 May;89(5):1580-1583. doi: 10.1177/00031348211067999. Epub 2022 Jan 3.

Abstract

Purpose: To determine whether time interval between hemi-thyroidectomy and subsequent completion thyroidectomy impacts outcomes.

Methods: Retrospective review of 68 patients having completion thyroidectomy from August 2012 to December 2019. Patients were separated into two groups based on the time interval between surgeries: early (≤10 days) or delayed (≥90 days).

Results: Patients who underwent delayed completion thyroidectomy (n = 17) had significantly higher rates of hypocalcemia and/or hypoparathyroidism (P = .03) and higher rates of requiring postoperative hospitalization (P=.07) compared to those who underwent early completion thyroidectomy (n = 51). Delayed completion had significantly lower risk of developing one or more of dysphonia, dysphagia, or vocal cord paresis postoperatively (P=.02). No patients developed hematoma or wound infection.

Conclusions: Delayed completion thyroidectomy is associated with increased rates of hypocalcemia, but lower rates of dysphonia and dysphagia. Given the low risk of long-term complications in both groups, it may be beneficial to perform completion thyroidectomy early in order to expedite cancer treatment.

Keywords: completion thyroidectomy; hemi-thyroidectomy; hypocalcemia; interval; thyroid cancer.

MeSH terms

  • Deglutition Disorders* / epidemiology
  • Deglutition Disorders* / etiology
  • Dysphonia* / complications
  • Dysphonia* / surgery
  • Humans
  • Hypocalcemia* / epidemiology
  • Hypocalcemia* / etiology
  • Hypoparathyroidism* / epidemiology
  • Hypoparathyroidism* / etiology
  • Hypoparathyroidism* / surgery
  • Postoperative Complications / etiology
  • Retrospective Studies
  • Thyroid Neoplasms* / complications
  • Thyroid Neoplasms* / surgery
  • Thyroidectomy / adverse effects