Redroot pigweed is a well-known allelopathic weed worldwide with diverse organic compounds which involving in its allelopathic interactions as well. Preliminary tests of redroot pigweed extract against leukemia and various human phatogenic microorganisms revealed that amaranth extract inhibits the viability and proliferation of NB4 cells in a time- and dose-dependent manner and has an excellent anti-bacterial effect on gram-positive bacteria and Candida fungi. Interestingly, the anti-luekemia effects of redroot pigweed is reported for the first time. Phytochemical analysis of redroot pigweed extract, led to the identification amaranth bioactive compounds that largely were including terpenoid compounds (51.71%) as the main group and Carvacrol (11.33%) was the key compound. Redroot pigweed contains various organic compounds with allelopathic and therapeutic properties and current investigation is a promising revelation for the pharmaceutical importance of this plant.
Keywords: GC–MS analysis; Redroot pigweed; acute promyelocytic leukemia; allelopathy; organic compounds; therapeutic properties.