New therapies for nontuberculous mycobacterial lung infection

Curr Opin Infect Dis. 2022 Apr 1;35(2):176-184. doi: 10.1097/QCO.0000000000000815.

Abstract

Purpose of review: Although nontuberculous mycobacterial pulmonary disease is increasing in incidence, outcomes remain less than optimal highlighting the unmet need for developing novel therapies.

Recent findings: Several new antibiotic formulations, novel antibiotics, and novel nonantibiotic treatments have recently demonstrated positive results in treating nontuberculous mycobacterial pulmonary disease.

Summary: Promising novel therapies are currently under investigation fueling much needed interest and enthusiasm in the nontuberculous mycobacterial pulmonary disease space and will hopefully lead to improved understanding and outcomes in this complex disease.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Humans
  • Lung / microbiology
  • Lung Diseases* / drug therapy
  • Lung Diseases* / microbiology
  • Mycobacterium Infections, Nontuberculous* / drug therapy
  • Opportunistic Infections* / drug therapy

Substances

  • Anti-Bacterial Agents