Examining the Relationships Between Air Pollutants and the Incidence of Acute Aortic Dissection with Electronic Medical Data in a Moderately Polluted Area of Northwest China

Abstract

This paper explored whether air pollutants influenced acute aortic dissection (AAD) incidence in a moderately polluted area. A total of 494 AAD patients' data from 2013 to 2016 were analyzed. The results showed that AAD had the strongest associations with $P{M}_{10}$, $S{O}_2$, $N{O}_2$, $CO$, and $O_3$ on the day before an AAD incident (lag1) and with $P{M}_{2.5}$ two days before an incident (lag2) in single-pollutant model. In the three-pollutant model, $P{M}_{10}$ was associated with the highest risk of adverse effects (RR = 1.37, 95% CI: 1.22, 1.53), whereas $P{M}_{2.5}$ was associated with the lowest risk (RR = .83, 95% CI: .79, .88). Both $P{M}_{2.5}$ and $P{M}_{10}$ were affected by season, and $S{O}_2$ was significantly different between heating and non-heating seasons as well. This study revealed significant associations between short-term $P{M}_{2.5}$, $P{M}_{10}$, and $S{O}_2$ exposure and daily AAD incidence, showing that $P{M}_{10}$ and $S{O}_2$ were strong predictors of AAD incidence in a moderately polluted area.

Keywords: acute aortic dissection; air pollution; incidence risk; moderately pollution; seasonal difference.