Photodynamic and Photothermal Therapy of Hepatocellular Carcinoma

Zhe Fan; Chengjun Zhuang; Shuang Wang; Yewei Zhang

doi:10.3389/fonc.2021.787780

Photodynamic and Photothermal Therapy of Hepatocellular Carcinoma

Front Oncol. 2021 Dec 7:11:787780. doi: 10.3389/fonc.2021.787780. eCollection 2021.

Authors

Zhe Fan^{1

2}, Chengjun Zhuang³, Shuang Wang⁴, Yewei Zhang⁵

Affiliations

¹ Department of General Surgery, the Third People's Hospital of Dalian, Dalian Medical University, Dalian, China.
² Department of Central Laboratory, the Third People's Hospital of Dalian, Dalian Medical University, Dalian, China.
³ Department of Critical Care Medicine, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
⁴ Department of Endocrinology, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
⁵ Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Abstract

Hepatocellular carcinoma (HCC) is the most common primary liver tumor. It is ranked the sixth most common neoplasm and the third most common cause of cancer mortality. At present, the most common treatment for HCC is surgery, but the 5-year recurrence rates are still high. Patients with early stage HCC with few nodules can be treated with resection or radiofrequency ablation (RFA); while for multinodular HCC, transarterial chemoembolization (TACE) has been the first-line treatment. In recent years, based on medical engineering cooperation, nanotechnology has been increasingly applied to the treatment of cancer. Photodynamic therapy and photothermal therapy are effective for cancer. This paper summarizes the latest progress of photodynamic therapy and photothermal therapy for HCC, with the aim of providing new ideas for the treatment of HCC.

Keywords: hepatocellular carcinoma; photodynamic therapy; photothermal therapy; review; treatment.

Publication types

Review