Rapid measurement of T1*-T2* relaxation correlation with a Look-Locker sequence

Jiangfeng Guo; Mohammad Sadegh Zamiri; Bruce J Balcom

doi:10.1016/j.jmr.2021.107123

Rapid measurement of T₁-T₂ relaxation correlation with a Look-Locker sequence

J Magn Reson. 2022 Feb:335:107123. doi: 10.1016/j.jmr.2021.107123. Epub 2021 Dec 9.

Authors

Jiangfeng Guo¹, Mohammad Sadegh Zamiri¹, Bruce J Balcom²

Affiliations

¹ UNB MRI Centre, Department of Physics, University of New Brunswick, Fredericton, New Brunswick E3B 5A3, Canada.
² UNB MRI Centre, Department of Physics, University of New Brunswick, Fredericton, New Brunswick E3B 5A3, Canada. Electronic address: bjb@unb.ca.

PMID: 34942574
DOI: 10.1016/j.jmr.2021.107123

Abstract

Measurement of longitudinal-transverse (T₁-T₂*) relaxation may be time-consuming for samples with a long T₁ lifetime. In this work, a fast measurement method of T₁*-T₂* relaxation correlation was presented based on a saturation recovery Look-Locker sequence. T₁* is the effective T₁ lifetime. The T₁ lifetime can be calculated from the measured T₁* lifetime and acquisition parameters. The new measurement method was verified by numerical simulation. Three representative samples, corn starch, Advil caplets, and shale in the fields of food, pharmaceutics, and energy, were employed as test samples. Comparisons of T₁*-T₂* and T₁-T₂* relaxation correlations show that the new two-dimensional magnetic resonance pulse sequence works well, with a high collection efficiency and good accuracy.

Keywords: Advil caplets; Corn starch; Look-Locker sequence; Magnetic resonance; Shale; T(1)*–T(2)* relaxation correlation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Computer Simulation
Magnetic Resonance Imaging* / methods
Magnetic Resonance Spectroscopy / methods
Reproducibility of Results