Analytical and numerical comparisons of two methods of estimation of additive × additive × additive interaction of QTL effects

J Appl Genet. 2022 May;63(2):213-221. doi: 10.1007/s13353-021-00676-7. Epub 2021 Dec 23.

Abstract

This paper presents the analytical and numerical comparison of two methods of estimation of additive × additive × additive (aaa) interaction of QTL effects. The first method takes into account only the plant phenotype, while in the second we also included genotypic information from molecular marker observation. Analysis was made on 150 doubled haploid (DH) lines of barley derived from cross Steptoe × Morex and 145 DH lines from Harrington × TR306 cross. In total, 153 sets of observation was analyzed. In most cases, aaa interactions were found with an exert effect on QTL. Results also show that with molecular marker observations, obtained estimators had smaller absolute values than phenotypic estimators.

Keywords: Barley; Doubled haploid (DH) lines; Genetic interactions; QTL interaction; Statistical methods.

MeSH terms

  • Genotype
  • Haploidy
  • Hordeum* / genetics
  • Phenotype
  • Quantitative Trait Loci*