Functional Hydrogel Dressings for Treatment of Burn Wounds

Wentao Shu; Yinan Wang; Xi Zhang; Chaoyang Li; Hanxiang Le; Fei Chang

doi:10.3389/fbioe.2021.788461

Functional Hydrogel Dressings for Treatment of Burn Wounds

Front Bioeng Biotechnol. 2021 Dec 6:9:788461. doi: 10.3389/fbioe.2021.788461. eCollection 2021.

Authors

Wentao Shu¹, Yinan Wang^{1

2}, Xi Zhang³, Chaoyang Li⁴, Hanxiang Le⁴, Fei Chang⁴

Affiliations

¹ Department of Biobank, Division of Clinical Research, The First Hospital of Jilin University, Changchun, China.
² Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education, The First Hospital of Jilin University, Changchun, China.
³ Department of Burn Surgery, The First Hospital of Jilin University, Changchun, China.
⁴ Department of Orthopedics, The Second Hospital of Jilin University, Changchun, China.

Abstract

The therapy of burns is a challenging clinical issue. Burns are long-term injuries, and numerous patients suffer from chronic pain. Burn treatment includes management, infection control, wound debridement and escharotomy, dressing coverage, skin transplantation, and the use of skin substitutes. The future of advanced care of burn wounds lies in the development of "active dressings". Hydrogel dressings have been employed universally to accelerate wound healing based on their unique properties to overcome the limitations of existing treatment methods. This review briefly introduces the advantages of hydrogel dressings and discusses the development of new hydrogel dressings for wound healing along with skin regeneration. Further, the treatment strategies for burns, ranging from external to clinical, are reviewed, and the functional classifications of hydrogel dressings along with their clinical value for burns are discussed.

Keywords: antibacterial; burn wound; emergency temporary coverage; factors promoting wound healing; hydrogel dressing; stem cells.

Publication types

Review