Hyperventilation is common in pulmonary arterial hypertension and may be related to autonomic imbalance. Patients underwent exercise testing and hyperoxic breathing before and after bisoprolol treatment. We found that neither beta blocker treatment nor hyperoxic breathing in patients reduced hyperventilation at rest and during exercise, although it reduced heart rate.
Keywords: autonomic imbalance; beta blocker; hyperventilation; pulmonary hypertension; sympathetic nervous system.
© The Author(s) 2021.