Viral Respiratory Infections: New Tools for a Rapid Diagnosis

Semin Respir Crit Care Med. 2021 Dec;42(6):747-758. doi: 10.1055/s-0041-1739306. Epub 2021 Dec 16.

Abstract

Respiratory tract infection is one of the most common diseases in human worldwide. Many viruses are implicated in these infections, including emerging viruses, such as the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Identification of the causative viral pathogens of respiratory tract infections is important to select a correct management of patients, choose an appropriate treatment, and avoid unnecessary antibiotics use. Different diagnostic approaches present variable performance in terms of accuracy, sensitivity, specificity, and time-to-result, that have to be acknowledged to be able to choose the right diagnostic test at the right time, in the right patient. This review describes currently available rapid diagnostic strategies and syndromic approaches for the detection of viruses commonly responsible for respiratory diseases.

Publication types

  • Review

MeSH terms

  • COVID-19 / diagnosis
  • COVID-19 / virology
  • Early Diagnosis*
  • Humans
  • Respiratory Tract Infections / diagnosis*
  • Respiratory Tract Infections / virology*
  • SARS-CoV-2 / isolation & purification
  • Sensitivity and Specificity
  • Time Factors