Fecal microbiota relationships with childhood obesity: A scoping comprehensive review

Obes Rev. 2022 Jan:23 Suppl 1:e13394. doi: 10.1111/obr.13394. Epub 2021 Dec 15.

Abstract

Childhood obesity is a costly burden in most regions with relevant and adverse long-term health consequences in adult life. Several studies have associated excessive body weight with a specific profile of gut microbiota. Different factors related to fecal microorganism abundance seem to contribute to childhood obesity, such as gestational weight gain, perinatal diet, antibiotic administration to the mother and/or child, birth delivery, and feeding patterns, among others. This review reports and discusses diverse factors that affect the infant intestinal microbiota with putative or possible implications on the increase of the obesity childhood rates as well as microbiota shifts associated with excessive body weight in children.

Keywords: STOP project; childhood obesity; dysbiosis; microbiota.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Child
  • Female
  • Gastrointestinal Microbiome*
  • Gestational Weight Gain*
  • Humans
  • Infant
  • Microbiota*
  • Pediatric Obesity*
  • Pregnancy
  • Weight Gain